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Bulletin of Pharmaceutical Research 2014;4(2):72-80
Kumar V. Topological models for the prediction of tyrosine kinase inhibitory activity of 4-anilinoquinazolines. Bull. Synthesis, characterization and in vitro antimicrobial activity of novel 4,4′-bis[3-chloro-4-aryl-azetidin-2-one-1-yl]diphenyl sulphones.
File link: http://journal.appconnect...2014/05/ReprintBPR093.pdf
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Go To Link - Bulletin of Pharmaceutical Research 2014;4(2):72-80
Enhances the Ability of 4-Anilinoquinazolines Inducing Apoptosis
Complexation with Organometallic Ruthenium Pharmacophores Enhances the Ability of 4-Anilinoquinazolines Inducing Apoptosis. 2. Synthesis and characterization of 4-anilinoquinazoline derivatives.
File link: http://www.rsc.org/suppdata/cc/c3/c3cc43000f/c3cc43000f.pdf
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Go To Link - Enhances the Ability of 4-Anilinoquinazolines Inducing Apoptosis
QSAR Studies of 4-Anilinoquinazolines with Antimalarial Activity
In the present work, we report quantitative structure-activity relationship (QSAR) analysis of series of 57 6-ureido-4-anilinoquinazolines derivatives with antimalarial activity by applying linear free energy related (LFER) approach of Hansch.
File link: https://www.derpharmachem...y-a-hansch-approaches.pdf
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Go To Link - QSAR Studies of 4-Anilinoquinazolines with Antimalarial Activity
Amination of Aryl Halides and Aryl Triates
23.30 Outline syntheses of the following compounds from the indicated starting materials. (a) p-iodoanisole from phenol and any other reagents. (b) m-bromoiodobenzene from nitrobenzene. C. Amination of Aryl Halides and Aryl Triates.
File link: http://www.saplinglearning.com/media/loudon/loudon5ech23sec11.pdf
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Go To Link - Amination of Aryl Halides and Aryl Triates
Medicinal chemistry
For this reason, a series of 2-amino-4-anilinoquinazolines was designed, synthesized and biologically assessed (Figure 1). Chemistry. The synthesis of the 4-chloro-2-aminoquinazoline (7) is illustrated in Figure 2. Reaction of commercial methyl 4...
File link: https://www.omicsonline.o...ves-2161-0444.1000067.pdf
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Quinazoline derivatives: synthesis
Copper-catalyzed reaction Aryl ether, alkyl ether, aryl amine, alkyl amine, aryl sulfide, alkyl sulfide, etc., which are all very important structural fragments in many. 6-Substituted-4-anilino quinazolines with irreversible binding property with EGFR were synthesized by Vasdev et al., starting from [18 F]...
File link: https://link.springer.com/content/pdf/10.1186/1752-153X-7-95.pdf
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Go To Link - Quinazoline derivatives: synthesis
University | Quinazoline (I)
In 2010, Nandi79 et. al., synthesized some of 4-anilino quinazoline derivatives and they showed anticancer activity. 109 The above same workers289 in 2000, also reported the synthesis of 4-arylamino quinazolines and 2-aryl-4-arylaminoquinazolines.
File link: http://shodhganga.inflibn.../20445/9/09_chapter 2.pdf
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Go To Link - University | Quinazoline (I)
Complexes Bearing EGFR-Inhibiting 4-Anilinoquinazoline Ligands
Dual-Targeting Organometallic Ruthenium(II) Anticancer Complexes Bearing EGFR-Inhibiting 4-Anilinoquinazoline Ligands. Yang Zhang, Wei Zheng,* Qun Luo, Yao Zhao, Erlong Zhang, Suyan Liu, and Fuyi Wang*.
File link: http://www.rsc.org/suppdata/c5/dt/c5dt01430a/c5dt01430a1.pdf
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Go To Link - Complexes Bearing EGFR-Inhibiting 4-Anilinoquinazoline Ligands
An Efficient Synthesis of Tetrazolo Indolo Quinazolines
Interest in quinazoline chemistry has increased manifolds because of its association in cancer chemotherapy. All these studies were directed toward synthesizing quinazolines that 2-Aryl-4-oxo-4H-benzo [d] [1, 3] oxazines 1. The method of Hirwe et.al. 19-21 was followed for the preparation of 1.
File link: http://chemistry-journal....OURNAL-CHJV08I04P0693.pdf
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Go To Link - An Efficient Synthesis of Tetrazolo Indolo Quinazolines